Abstract

Diarrhea is a worldwide health concern. This study was conducted to evaluate the anti-diarrheal activity of two commonly used medicinal plants of Bangladesh Averrhoa carambola and Averrhoa bilimbi. The Percentage inhibition defecation of A. carambola is 10.3% and 69.2% (p = 0.0001) in the dosages of 25 mg/kg and 50 mg/kg respectively. A. bilimbi inhibited diarrhea 2.6% and 8% at low and high dosage respectively. The percentage inhibition of loperamide (3mg/kg) is 74.4% (p = 0.001). Results shows that the effect of Averrhoa carambola shows a dose-dependent relationship, wherein higher doses exert much stronger effects compared to lower doses. On the other hand, the methanolic extract of Averrhoa bilimbi does not show any anti diarrheal activity at the dose of 25 mg/kg and 50 mg/kg. Further research should be done to determine its therapeutic dose.